American Medical Association

Evaluating the safety profile of mifepristone

April 22, 2024 - Mifepristone, commonly known as the abortion pill, is a medication used primarily for medically induced abortions as well as the management of Cushing's syndrome and uterine leiomyomas. Since its approval in 2000, mifepristone has been the subject of extensive research and scrutiny, although it has a favorable safety profile.  The safety evaluation of mifepristone has gained...

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Only 3.3% of NIH-Funded Pediatric Clinical Trials Data Is Reusable

by Veronica Salib

In a research letter published in JAMA Network Open on July 25, 2023, scientists evaluated data availability from pediatric clinical trials funded by the National Institutes of Health (NIH). According...

FDA Approves Over-the-Counter, Nonprescription Birth Control

by Veronica Salib

After months of deliberation, the United States Food and Drug Administration (FDA) approved the first hormonal oral contraceptive for non-prescription over-the-counter (OTC) sale. This historical...

Adverse Birth Outcome Linked to Forever Chemical Exposure in Pregnancy

by Veronica Salib

On May 31, 2023, JAMA Network Open published an article detailing the impacts of perfluoroalkyl and polyfluoroalkyl substance (PFAS) exposure on birth outcomes. Researchers determined that exposure to...

High Prescription Drug Costs Lead Older Patients to Ration Medication

by Veronica Salib

While not a new concept, drug rationing across the United States has become an increasingly critical issue. In another tale about the dangers of high prescription drug costs, researchers published an...

How Do NIH Funding Requirements Impact Researcher Demographics?

by Veronica Salib

An analysis of the impact of the National Institutes of Health (NIH) funding requirements determined that they improve diversity in medical scientist training programs (MSTPs). The data revealed more...

Other Countries Refused 47 FDA-Approved Drugs in the United States

by Veronica Salib

An investigation published in JAMA Internal Medicine assessed FDA-approved drugs and regulatory decisions made in other countries. In particular, the study focused on regulation and health technology...

Scientists at the University of Washington Study Breast Cancer Vaccine

by Veronica Salib

Early phase studies by scientists at the University of Washington found that a plasmid DNA breast cancer vaccine may produce favorable outcomes, generating anti-tumor immunity. The study, published in...

COVID Vaccines Have Prevented 3,255,656 Deaths

by Veronica Salib

COVID vaccines and vaccination campaigns have had unparalleled benefits throughout the COVID-19 pandemic. Many argue that vaccines have been the most effective public health tool against infection....

How to Improve Regulatory Measures for Dietary Supplements

by Veronica Salib

Across every pharmacy, grocery store, and convenience store in the United States, dietary supplements — in some shape or form — line the shelves. Many patients have the misconception that because these products are sold and...

Biosimilars in the US Cost 2.74 Times More Than in Other Countries

by Veronica Salib

Biosimilars, biologic products similar to brand-name biologics, are praised as a less expensive alternative for patients with chronic diseases requiring biologics. Many providers and healthcare experts...

Understanding the Correlation Between COVID-19 and Flu Vaccination

by Veronica Salib

While less than ideal, the progression of the COVID-19 pandemic has presented public health officials with data to analyze on vaccine uptake. In a recent research letter published in JAMA Network Open,...

Study Finds Increased Prevalence of Nonpharmacological Pain Treatment

by Veronica Salib

Following a publication earlier this year that analyzed patterns in prescribing nonopioid pain medication, JAMA Network Open published an article on November 7, 2022, which compared trends in...

COVID-19 Vaccine Side Effects Are Associated with Antibody Response

by Veronica Salib

As with any vaccine, the COVID-19 vaccine led to some common side effects. However, the severity of these side effects varies by individual. In a recent study published in JAMA Network Open,...

Motivational Interventions May Improve SUD Recovery

by Veronica Salib

On October 21, 2022, JAMA Network Open published the results of a randomized clinical trial on the effects of emergency room motivational interventions on substance use disorders (SUD). Using a cohort...

Nearly 13% of Oral Anticancer Prescriptions Are Not Received

by Veronica Salib

The financial burden associated with cancer treatment and recovery is significant. Many patients struggle to obtain medicines and continued care. According to a recent study published in JAMA Network...

AMA Analysis Finds Variations in PBM Competition

by Veronica Salib

In a recent analysis written by José R. Guardado, PhD, for the AMA, he analyzed the competition against drug intermediaries, referred to as pharmacy benefit managers (PBMs). In the report,...

Drug Costs Are Not Justified by Research and Development Costs

by Veronica Salib

It’s no secret that drug costs in the United States have continued to increase in the past few years. The Kaiser Family Foundation states that between 2019 and 2022, 48% of prescription drugs had...

Digital Health Tools Are Perceived as an Advantage to 93% of Physicians

by Veronica Salib

Between 2016 and 2022, the AMA surveyed approximately 1,300 providers in the United States for AMA Digital Health Research. This data collected information on motivations and requirements for digital...

Pregnant and Lactating Individuals Tolerate COVID Vaccine Boosters

by Veronica Salib

As new COVID boosters are approved and distributed, understanding how they affect pregnant and lactating individuals will impact public health policies, educational efforts, and provider distribution....

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