Clinical Trials & Research News

Metformin use is associated with reduced cancer risk

April 25, 2024 - Two recent studies published in the Journal of the National Cancer Institute have correlated metformin use with lower cancer risks, implying that the drug may offer some protection against the illness. The first of these studies was a systematic review and meta-analysis published earlier this year. Researchers used databases such as PubMed,...

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DMARDs for rheumatoid arthritis linked to lower dementia risk

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Research published in Rheumatic & Musculoskeletal Disease found that patients with rheumatoid arthritis (RA) who were taking biological disease-modifying antirheumatic drugs (DMARDs) had a 24%...

Age-adjusted drug overdose deaths stabilized from 2021 to 2022

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A CDC analysis noted that between 2021 and 2022, the age-adjusted rate of drug overdose deaths did not change significantly, a variation from previous years where the rates climbed overall. However,...

WHO reports increasing rates of HIV drug resistance to dolutegravir

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Earlier this week, the World Health Organization (WHO) issued a news release stating that there are increased trends in human immunodeficiency virus (HIV) drug resistance to dolutegravir. Despite this...

NIH Launches Cancer Screening Research Network for Early Detection

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On Wednesday, February 21, 2024, the NIH launched a clinical trial network for evaluating new cancer detection technologies or methods called the Cancer Screening Research Network (CSRN), which will...

Injectable HIV ART Is an Effective Alternative to Oral Medications

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On February 21, 2024, the NIH issued a press announcement revealing that long-acting injectable antiretroviral therapy (ART) using cabotegravir and rilpivirine was more effective than oral ART at...

Almost Half of Infants in the US Have Received the RSV Vaccine

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Last week, the CDC updated data on respiratory syncytial virus (RSV) vaccine uptake in the United States, revealing that almost half of infants in the US have been vaccinated. Additional data provided...

10% of Premature Births Linked to Phthalate Exposure In Utero

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Earlier this week, researchers revealed that approximately 10% of premature births in the United States are linked to prenatal phthalate exposure in a study published in the Lancet Planetary...

GLP-1 Medication Use Is Linked with Lower Anxiety, Depression Rates

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On Tuesday, February 6, 2024, Epic Research published the results of a dual-team Cosmos study, highlighting that taking certain glucagon-like peptide-1 (GLP-1) receptor agonists may reduce the chances...

GLP-1 Receptor Agonists Reduce 24-Hour Ambulatory Blood Pressure

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On Monday, February 5, 2024, a research letter published in Hypertension highlighted the benefit of tirzepatide in managing high blood pressure using data from the SURMOUNT study. The letter notes a...

Mislabeled Packaging Results in Recalled ADHD Medication

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On January 24, 2024, Azurity Pharmaceuticals sent an announcement to the United States FDA recalling Zenzedi, a brand name for 30 mg dextroamphetamine sulfate tablets, for mislabeled packaging. The...

Vertex Non-Opioid Drug Is an Effective Pain Management Medication

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On Tuesday, January 30, 2024, Vertex Pharmaceuticals issued a press release announcing that VX-548, its non-opioid pain management drug, effectively reduced pain compared to the placebo across multiple...

Patients Maintain Weight Loss One Year After Discontinuing GLP-1 Drugs

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Earlier this week, Epic Research published a dual-team Cosmos study assessing how stopping glucagon-like peptide-1 (GLP-1) receptor agonists, sometimes called GLP-1 drugs, can impact long-term weight...

Semaglutide Reduces Weight in Patients with Failed Bariatric Surgery

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According to a study published in Obesity, semaglutide effectively triggers weight loss in severely obese patients, including those who have had bariatric surgery to manage weight but have not yielded...

Researchers Reveal Positive Data on New Antibiotic for Super Gonorrhea

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On November 1, 2023, the Global Antibiotic Research and Development Partners (GARDP) and Innoviva Specialty Therapeutics, a subset of Innoviva Inc, issued a co-authored press release announcing that a...

Taking Anti-Inflammatory Medication with Plan B Improves Effectiveness

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A new study published in the Lancet provides a new route for improving the effectiveness of oral emergency contraceptives. According to the study, taking an anti-inflammatory pill alongside Plan B...

Zuranolone Effectively and Safely Treats Postpartum Depression

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A study published in the American Journal of Psychiatry on July 26, 2023, proved that zuranolone could effectively and safely treat postpartum depression. The study supports the priority review granted...

Only 3.3% of NIH-Funded Pediatric Clinical Trials Data Is Reusable

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In a research letter published in JAMA Network Open on July 25, 2023, scientists evaluated data availability from pediatric clinical trials funded by the National Institutes of Health (NIH). According...

Melanoma Drugs Repurposed Can Shrink Rare Brain Tumors

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A study published last week in the New England Journal of Medicine concluded that BRAF–MEK inhibitors — traditionally used in melanoma treatment — can shrink papillary...

Majority of Patients Quit Weight-Loss Drugs Like Wegovy Within First Year

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A recent cost analysis shared with Reuters showed that only a third of patients continued to use popular glucagon-like peptide-1 (GLP-1) compounds a year after initial prescription. Healthcare costs...

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