Drug Development

Hormonal Male Birth Control Product Reaches Late-Phase Clinical Trials

by Veronica Salib

The only male forms of birth control currently available are condoms and vasectomies. With a limited choice in male birth control, contraception typically falls on the child-bearing individual. This...

How Pharmaceutical Patents Contribute to Increased Drug Costs

by Veronica Salib

In the United States, drug prices have soared in recent years. The pharmaceutical industry and medicine, in general, have been criticized for these rising drug costs. Beyond the associated financial burden, inflated medication costs also...

A History of Antivirals: Mechanisms, Classes, and Subtypes

by Veronica Salib

Antivirals have rapidly become a popular topic with their implications in treating COVID-19. Understanding antivirals, their mechanisms, classes, and subtypes is an essential part of being able to treat viral infections such as the...

Astellas and Seagen Announce Results on a Drug for Urothelial Cancer

by Veronica Salib

According to a recent press release, Astellas and Seagen have teamed up to develop a combined treatment for urothelial cancer in patients who are ineligible to receive cisplatin chemotherapy. The new...

Orexo Pharmaceuticals Announces Nasal Adrenaline Clinical Development

by Veronica Salib

On July 5, 2022, Orexo Pharmaceuticals announced plans to begin clinical development of a nasal adrenaline rescue medication. This study, called OX640-001, is looking at OX640, which is a nasal...

Decibel Therapeutics Announces Results of DB-020 Clinical Trial

by Veronica Salib

At the end of June, Decibel Therapeutics announced success in the phase 1b clinical trials on DB-020 for cancer patients receiving cisplatin chemotherapy. DB-020 is a sodium thiosulfate (STS) drug...

FDA Releases Drug Safety Communication regarding Cancer Drug, Copiktra

by Veronica Salib

On June 30, the FDA released a drug safety communication that warned against the risks associated with Copiktra. Copiktra, also called duvelisib, is a cancer drug used to treat relapsed or...

FDA Approves New Treatment for Large B-Cell Lymphoma

by Veronica Salib

Recently, the FDA approved a new second-line treatment for large B-cell lymphoma (LBCL). Lisocabtagene maraleucel is the generic name for Breyanzi, developed and marketed by Juno Therapeutics. As a...

FDA Approves New Weight Management Drug for Kids over 12

by Veronica Salib

Recently, the FDA approved Qsymia for chronic weight management in pediatric patients over 12 years old. Qsymia is an extended-release pill composed of phentermine and topiramate. The drug’s...

Women Are Underrepresented in Clinical Trials, Leading to Health Inequity

by Veronica Salib

Contemporary Clinical Trials published a study by researchers at the Brigham and Women’s Hospital that shows women were underrepresented in clinical trials. This conclusion may be contributing to...

FDA Expanded Approval of Skyrizi for Treatment of Crohn’s Disease

by Veronica Salib

The FDA recently approved Skyrizi as a treatment for moderate to severely active Crohn’s disease. Crohn’s disease is an inflammatory bowel disease (IBD) with many painful symptoms that can...

FDA Approved Weight-Management Treatment for Bardet–Biedl Syndrome

by Veronica Salib

The FDA recently approved the Imcivree (setmelanotide) injection as a weight-management treatment for adults and children over 6 with Bardet–Biedl Syndrome (BBS). BBS is a relatively...

Could the Approval of Albrioza by Health Canada for ALS Impact the FDA Ruling?

by Veronica Salib

This week, Health Canada announced its approval of Albrioza (created by Amylyx Pharmaceuticals) for the treatment of ALS. It has been the only newly approved treatment for ALS since 2018. The drug is...

Olumiant Becomes the First FDA-Approved Systemic Treatment for Alopecia Areata

by Veronica Salib

Monday’s FDA approval of Olumiant for the treatment of Alopecia Areata (AA) marks a historical change in the procedures used to address Alopecia Areata as it is the first systemic therapy for the...

Academia Partners with Pharma to Discover New SARS-CoV-2 Drug Treatments

by Alivia Kaylor

The National Institutes of Health (NIH) and the National Institutes of Allergy and Infectious Disease (NIAID)’s Antiviral Drug Discovery (AViDD) Centers for Pathogens of Pandemic Concern program...

FDA Lifts Clinical Hold on Gilead’s HIV Treatment, Lenacapavir

by Samantha McGrail

FDA recently lifted the clinical hold on Gilead’s investigational new drug application (IND) to evaluate injectable lenacapavir for HIV treatment and HIV pre-exposure prophylaxis...

Novo Nordisk, Flagship to Develop Rare Disease Treatments

by Samantha McGrail

Novo Nordisk and Flagship Pioneering recently collaborated to create a portfolio of novel research programs to develop transformation metabolic and rare disease treatments. The companies will apply...

AstraZeneca to Open Drug Research, Development Site in MA

by Samantha McGrail

AstraZeneca recently announced plans to open a new drug research and development site at the heart of Cambridge, MA, for itself and Alexion’s new corporate headquarters. The strategic center...

Dr. Vishal Sikka to Join GSK as Non-Executive Director

by Samantha McGrail

GSK recently announced Vishal Sikka, MD, CEO of Vinai Systems, as non-executive board director. Sikka joins GSK from the Haleon demerger and as a board member of Oracle Corporation and BMW. He...

J&J Launches Satellite Center to Tackle Antimicrobial Resistance

by Samantha McGrail

Johnson & Johnson recently launched the J&J Satellite Center for Global Health Discovery (Satellite Center) to tackle the present and the rising threat of antimicrobial resistance (AMR) with a...