Drug Discovery

Eli Lilly, Lycia Collaborate to Discover Targeted Drug Candidates

by Samantha McGrail

Eli Lilly and Company recently entered into a multi-year research collaboration and licensing agreement with Lycia Therapeutics to discover, deliver, and commercialize novel targeted drug...

Bayer Enters Pharma Acquisition Deal for Undruggable Targets

by Samantha McGrail

Bayer recently entered into a pharma acquisition deal with Vividion Therapeutics to unlock high value, traditionally undruggable targets with precision therapeutics.  Vividion will leverage its...

Eli Lilly, Kumquat to Discover Drug Candidates for Tumors

by Samantha McGrail

Eli Lilly and Company and Kumquat Biosciences recently entered into a multi-year collaboration to discover, develop, and commercialize potential small molecule drug candidates that stimulate...

Amgen Enters Pharma Acquisition Deal to Develop New Biologics

by Samantha McGrail

Amgen recently entered into a pharmaceutical acquisition deal with Teneobio to discover and develop new biologics to treat various diseases across Amgen’s therapeutic areas.  Teneobio is a...

AstraZeneca, Regeneron to Develop Drug Candidates to Treat Obesity

by Samantha McGrail

AstraZeneca recently entered into a collaboration with Regeneron to research, develop, and commercialize small molecule drug candidates to treat obesity and related co-morbidities.  Specifically,...

Biogen’s Alzheimer’s Disease Drug Safe, Effective in Trial

by Samantha McGrail

Biogen recently announced that its Alzheimer’s disease drug, BIIB080, was safe and well-tolerated in patients with mild disease. The drug was developed in partnership with Ionis...

Biden Invests Over $3B to Boost COVID-19 Antiviral Development

by Samantha McGrail

The Biden Administration will invest over $3 billion to accelerate the discovery, development, and manufacturing of COVID-19 antiviral medicines. The initiative, called the Antiviral Program for...

Understanding Basic Principles of Pharmaceutical Drug Discovery

by Samantha McGrail

Drug discovery is a crucial part of the drug development pipeline, beginning with the identification of a disease target to the creation of lead compounds. According to Amanda Garner, PhD, Associate...

Thermo Fisher, UCSF Boost Manufacturing of Cell-Based Therapies

by Samantha McGrail

Thermo Fisher Scientific and the University of California (UCSF) recently formed a strategic alliance to accelerate the development and manufacturing of cell-based therapies. Under the terms of...

Eli Lilly Taps saRNA Research Tech from MiNA for Drug Discovery

by Samantha McGrail

Eli Lilly and Company and MiNA Therapeutics recently entered into a global research collaboration  that will leverage small activating RNA (saRNA) research technology for drug discovery. MiNA...

AI in the Pharma Industry: Current Uses, Best Cases, Digital Future

by Samantha McGrail

Pharmaceutical executives are looking for ways to leverage artificial intelligence and machine learning within the healthcare and the biotech industry. Reports show an increasing number of entities are...

Early COVID-19 Treatments Elicited No Real Benefits in Patients

by Samantha McGrail

A JAMA Network Open study found that COVID-19 treatments hydroxychloroquine and lopinavir-ritonavir failed to show any significant benefit in hospitalized patients. The study analyzed metrics such...

AstraZeneca Reports Positive Results in Cancer Drug Clinical Trial

by Samantha McGrail

AstraZeneca recently announced that its cancer drug, Calquence elicited positive responses in a Phase 2 clinical trial of mantle cell lymphoma patients.  The Phase 2 trial, ACE-LY-004, uncovered...

COVID-19 Drug Discovery for Early Treatment Lacking, But Needed

by Samantha McGrail

COVID-19 drug discovery efforts for early treatment of the virus in mild to moderate cases of the virus have been lacking even though successes now could mitigate the impact future outbreaks have on...

Boston Children’s Gets $65M for Drug Discovery Innovation

by Samantha McGrail

Boston Children’s Hospital and Deerfield Management Company recently announced a research collaboration aimed at advancing drug discovery and development to address rare and complex pediatric...

GSK, Vir Biotechnology Expand Phase 3 Study of COVID-19 Antibody

by Samantha McGrail

Vir Biotechnology and GSK recently announced the global expansion of a Phase 3 study evaluating their COVID-19 antibody, VIR-7831. The COMET-ICE study will evaluate VIR-7831 in patients who are at...

Systemic Corticosteroids Linked to Lower COVID-19 Mortality

by Samantha McGrail

In critically ill COVID-19 patients, administration of systemic corticosteroids compared with standard care was associated with lower 28-day all-cause mortality, according to a recent JAMA Network Open...

Remdesivir May Not Greatly Help Moderately Ill COVID-19 Patients

by Samantha McGrail

Although remdesivir showed clinical benefit in patients with severe COVID-19, it showed little benefit on clinical status for moderately ill COVID-19 patients , a recent JAMA Network Open study...

Bristol Myers Squibb Pays $475M to Acquire Immunotherapy Program

by Samantha McGrail

Bristol Myers Squibb recently announced it acquired Dragonfly Therapeutics’ investigational immunotherapy program for $475 million. Under the definitive agreement, Bristol Myers Squibb will be...