Research & Evidence

Comparing inflammatory bowel disease treatment options

March 26, 2024 - Last month, AbbVie sponsored several presentations and posters at the European Crohn's and Colitis Organization’s (ECCO) annual congress. Among these abstracts was the SEQUENCE study, which compared risankizumab and ustekinumab for treating inflammatory bowel disease (IBD). Marla Dubinsky, MD, lead study investigator, sat down with PharmaNewsIntelligence to discuss the...

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Gilead Announced Plans to Acquire CymaBay in a $4.3 Billion Deal

by Veronica Salib

On Monday, February 12, 2024, Gilead Sciences, a major pharmaceutical manufacturer, announced its plans to acquire CymaBay Therapeutics, a clinical-stage biopharmaceutical company with a strong liver...

NIH-Developed Antibodies Neutralize HIV in Animal Studies

by Veronica Salib

On January 17, 2024, the National Institutes of Health (NIH) issued a media advisory announcing the results of a proof-of-concept identifying three antibodies that protect against various human...

FDA Approves First Therapy for Progressing Desmoid Tumors

by Veronica Salib

On Monday, November 27, 2023, the United States Food and Drug Administration (FDA) approved Ogsiveo (nirogacestat), making it the first FDA-approved treatment for desmoid tumors. The drug is intended...

NIH Alters Grant Review Process, Focusing on Scientific Merit

by Veronica Salib

On October 19, 2023, the National Institutes of Health (NIH) announced plans to alter and simplify its grant review process, attempting to eliminate reputational bias in grant allocation. The updated...

A Look at California’s Newest Bans on Chemicals in Food

by Veronica Salib

On October 7, 2023, California Governor Gavin Newsom signed a bill prohibiting the manufacturing, sale, delivery, distribution, or carrying of food products for human consumption containing four presumably harmful chemicals: brominated...

Can Pharmaceutical Companies Ethically Sponsor Medical Education?

by Veronica Salib

The pharmaceutical industry plays a pivotal role in healthcare, driving innovation and providing new tools to optimize patient care and management. Despite the many benefits offered by pharmaceutical companies and manufacturers, there is...

Vaccinations Needed to Prevent COVID-19 ED Visits, Hospitalization

by Veronica Salib

The coronavirus pandemic has had detrimental impacts on communities across the United States, causing emergency department visits (ED visits), hospitalizations, long-term chronic diseases, financial losses, deaths, and more. The...

Melanoma Drugs Repurposed Can Shrink Rare Brain Tumors

by Veronica Salib

A study published last week in the New England Journal of Medicine concluded that BRAF–MEK inhibitors — traditionally used in melanoma treatment — can shrink papillary...

How Medical Affairs Impact the Pharmaceutical Industry

by Editorial Staff

Nearly every medical device or pharmaceutical company has a medical affairs team responsible for gathering scientific data and communicating it with leaders in the pharmaceutical industry. However, a...

Promising Results Seen in Pancreatic Cancer mRNA Vaccine Trials

by Veronica Salib

Adding to the significant progression of mRNA vaccines in cancer care, Memorial Sloan Kettering Cancer Center (MSKCC) researchers have announced promising results from a phase 1 clinical trial using...

Applying Artificial Intelligence, Machine Learning in Cancer Care

by Veronica Salib

Artificial intelligence (AI) and machine learning (ML) have become a growing component of nearly every industry. The ability to model and problem-solve using technology instead of trial and error has proven extremely valuable beyond the...

Department of Agriculture Licenses Lyme Vaccine for Use in Wild Mice

by Hayden Schmidt

Yesterday, the United States Department of Agriculture (USDA) conditionally licensed an oral vaccine for Borrelia burgdorferi, the bacteria that causes Lyme disease. LymeShield, the product...

Advancing Health Equity with Clinical Trial Diversity: Key Strategies

by Veronica Salib

Clinical trials are currently the gold standard for proving the efficacy and safety of new treatments for regulatory approval. Globally, clinical trial data supports medical decisions and drug development. Each year, hundreds of thousands...

How Do NIH Funding Requirements Impact Researcher Demographics?

by Veronica Salib

An analysis of the impact of the National Institutes of Health (NIH) funding requirements determined that they improve diversity in medical scientist training programs (MSTPs). The data revealed more...

Long-Acting Injectable Antiretroviral Therapy Suppresses HIV

by Veronica Salib

An ongoing study supported by the NIH in San Francisco assessed the efficacy of long-acting antiretroviral therapy (LA-ART), administered via injection, for treating HIV. The study compared LA-ART to...

Effectively Managing Clinical Trials, Recruitment, and Adaptive Trials

by Veronica Salib

Clinical trial significance and success throughout the COVID-19 pandemic have inspired the launch of clinical trial branches for existing companies, such as Walgreens, and multiple startups. However, it is critical to note that while some...

Alternatives to Animal Testing Models in Clinical and Biomedical Research

by Alivia Kaylor

Before the FDA Modernization Act 2.0 was passed in December 2022, the US government required that all investigational drugs be tested on animals before they could advance to human trials. Although this act does not ban animal testing, it...

Flexible Prescribing Did Not Increase Buprenorphine Overdose Deaths

by Veronica Salib

Despite common misconceptions, researchers published an article in JAMA Network Open noting that buprenorphine overdose-related deaths did not increase during the COVID-19 pandemic when providers were...

AHA Funds Research Network to Advance Clinical Trial Diversity

by Veronica Salib

Clinical trial diversity is a necessity for ensuring equitable access to healthcare. Clinical trial data is extrapolated and used to make regulatory decisions, including drug approval, dosages,...

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