Research & Evidence

6-in-1 Pediatric Vaccine from Merck, Sanofi Available Across US

by Samantha McGrail

Merck and Sanofi recently announced that their six-in-one combination pediatric vaccine is now available throughout the US.  Vaxelis is the first and only hexavalent combination vaccine available...

Moderna, Aldevron Expand Partnership for mRNA COVID-19 Vaccine

by Samantha McGrail

Moderna and Aldevron recently expanded their partnership to support Moderna’s mRNA COVID-19 vaccine and clinical development therapeutic pipeline.  Aldevron is a provider of plasmid DNA,...

Japan Grants AstraZeneca’s COVID-19 Vaccine Emergency Use

by Samantha McGrail

AstraZeneca’s COVID-19 vaccine, Vaxzevria, was recently granted emergency use in Japan for active immunization of individuals 18 years of age and older.  The Japanese Ministry of Health,...

Moderna’s mRNA COVID-19 Vaccine 100% Effective in Adolescents

by Samantha McGrail

Moderna recently announced that the Phase 2/3 study of its COVID-19 vaccine in adolescents met its primary immunogenicity endpoint, successfully bridging immune response to the adult...

FDA Approves Janssen’s Targeted Non-Small Cell Lung Cancer Therapy

by Samantha McGrail

FDA recently approved Janssen’s Rybrevant as the first targeted therapy for patients with subset of non-small cell lung cancer.  The agency approved the therapy based on a study of 81...

GSK-Medicago COVID-19 Vaccine Elicits High Antibody Responses

by Samantha McGrail

Medicago’s Coronavirus-Like Particle COVID-19 Vaccine Candidate (CoVLP) elicited significant humoral immune response across all age groups when administered in combination with GSK’s...

Abbott’s Navitor for Severe Aortic Stenosis Receives CE Mark

by Samantha McGrail

Abbott recently announced that it received CE Mark for its latest-generation transcatheter aortic valve implantation (TAVI) system, Navitor, for individuals with severe aortic stenosis in...

Top mRNA COVID-19 Vaccines 94% Effective, New CDC Data Shows

by Samantha McGrail

A multisite test-negative design case-control CDC study recently found that the mRNA COVID-19 vaccines from Pfizer and Moderna are highly effective against symptomatic coronavirus. The study analyzed...

Eli Lilly Taps saRNA Research Tech from MiNA for Drug Discovery

by Samantha McGrail

Eli Lilly and Company and MiNA Therapeutics recently entered into a global research collaboration  that will leverage small activating RNA (saRNA) research technology for drug discovery. MiNA...

Eli Lilly Takes on Digital Diabetes Care Management

by Samantha McGrail

Eli Lilly and Company recently signed strategic international agreements with four companies to advance connected solutions and streamline diabetes care management for individuals living with the...

Pfizer COVID-19 Vaccine Can be Used in Adolescents, FDA Says

by Samantha McGrail

FDA recently expanded the emergency use authorization for the Pfizer COVID-19 vaccine to include adolescents 12 through 15 years of age. The agency amended the original emergency use authorization...

Out-of-Pocket Costs for Brand-Name Medications Increased 15%

by Samantha McGrail

JAMA Network Open study found that change in brand-name medication prices for most commercially insured patients correlated with changes in out-of-pocket costs. In the study, nearly 53.7 percent of...

FDA Greenlights AstraZeneca’s Farxiga for Chronic Kidney Disease

by Samantha McGrail

FDA recently approved AstraZeneca’s Farxiga oral tablets to reduce the risk of kidney function decline, kidney failure, cardiovascular, death, and hospitalization for heart failure in adults with...

Few Drugs Make Half of Medicare Prescription Drug Spending

by Samantha McGrail

A Kaiser Family Foundation analysis recently found that a small number drugs accounted for a disproportionate share of Medicare prescription drug spending in 2019.  Researchers measured the share...

Early COVID-19 Treatments Elicited No Real Benefits in Patients

by Samantha McGrail

A JAMA Network Open study found that COVID-19 treatments hydroxychloroquine and lopinavir-ritonavir failed to show any significant benefit in hospitalized patients. The study analyzed metrics such...

COVID-19 Mortality Dropped as Drug Therapies Emerged

by Samantha McGrail

New COVID-19 drug therapies along with better clinical management of patients with SARS-CoV-2 infection may have contributed to reductions in in-hospital COVID-19 mortality rates, according to a recent...

FDA Rescinds EUA for Eli Lilly’s Monoclonal COVID-19 Antibody

by Samantha McGrail

FDA recently revoked the emergency use authorization that allowed for Eli Lilly & Company’s monoclonal COVID-19 antibody, bamlanivimab, to be used for coronavirus treatment in adults and...

FDA Approves Opdivo as First Immunotherapy for Gastric Cancer

by Samantha McGrail

FDA recently approved Opdivo, making it the first immunotherapy for initial treatment of patients with advanced or metastatic gastric cancer, gastroesophageal junction cancer, and esophageal...

Eli Lilly Asks FDA to Revoke the EUA for COVID-19 Antibody Drug

by Samantha McGrail

Eli Lilly and Company recently requested that FDA revoke the emergency use authorization for its COVID-19 antibody treatment. The FDA’s authorization has allowed providers to use 700 milligrams...

China Approves AstraZeneca’s Non-Small Cell Lung Cancer Drug

by Samantha McGrail

AstraZeneca recently announced that China approved its prescription drug, Tagrisso, for the treatment of patients with early-stage epidermal growth factor receptor-mutated (EGFRm) non-small cell lung...