Research & Evidence

Sanofi, GSK Halt Adjuvanted COVID-19 Vaccine Program

by Samantha McGrail

Sanofi and GSK recently announced they will  delay a program testing an adjuvanted COVID-19 vaccine after results from a Phase 1/2 study showed a low immune response in older adults. The...

Canada Opts to Double Doses of Moderna’s COVID-19 Vaccine

by Samantha McGrail

Moderna recently announced that the Canadian Government will now acquire an additional 20 million doses of its mRNA COVID-19 vaccine, bringing the total to 40 million doses.  The updated...

Moderna Launches Study of COVID-19 Vaccine in Adolescents

by Samantha McGrail

Moderna recently announced that the first adolescent patients have been dosed in the Phase 2/3 study of its mRNA-based COVID-19 vaccine, mRNA-1273. The randomized, controlled Phase 2/3 study will...

Roche to Include COVID-19 Antibody Test in Moderna’s Trials

by Samantha McGrail

Roche recently announced a partnership with Moderna to utilize the Elecsys COVID-19 antibody test in Moderna’s mRNA-1273 vaccine research clinical trials. The partnership will allow for easier...

Pfizer Reports Positive Data for Multiple Myeloma Antibody Drug

by Samantha McGrail

Pfizer recently announced that 83 percent of patients in the ongoing Phase 1 study of its investigational multiple myeloma antibody drug achieved clinical response at the highest dose level.  The...

Ovid Therapeutics Rare Disease Drug Fails in Phase 3 Study

by Samantha McGrail

Ovid Therapeutics recently announced that the Phase 3 clinical trial of its rare disease drug for the treatment of Angelman syndrome did not meet primary endpoints.  Specifically, OV101, or...

Eli Lilly, UnitedHealth Group Launch Study of COVID-19 Antibody

by Samantha McGrail

Eli Lilly and Company and UnitedHealth Group recently announced a partnership to conduct a pragmatic study of the COVID-19 antibody LY-CoV555 in high-risk individuals infected with the...

GSK Initiates Phase 3 Study of RSV Maternal Vaccine Candidate

by Samantha McGrail

GSK recently announced that it will begin a Phase 3 study investigating the safety and efficacy of its Respiratory Syncytial Virus (RSV) vaccine candidate for maternal immunization.  The...

Second Analysis Finds Moderna’s COVID-19 Vaccine 94.1% Effective

by Samantha McGrail

Moderna recently announced that a second primary analysis of its COVID-19 vaccine candidate, mRNA-1273, found a 94.1 percent vaccine efficiency against the coronavirus.  The Phase 3 study, COVE,...

Siemens Healthineers Launches Improved COVID-19 Antibody Test

by Samantha McGrail

Siemens Healthineers recently announced the launch of its COVID-19 antibody test, which has previously proven to measure neutralizing antibodies and has achieved CE Mark.  Notably, the SARS-CoV-2...

Placebo Elicits Same Side Effects As Cholesterol-Lowering Statins

by Samantha McGrail

An American Heart Association study recently found that patients taking cholesterol-lowering statin medication and patients taking a placebo reported the same side effects.  Specifically,...

Sanofi’s mRNA COVID-19 Vaccine Elicits High Antibody Levels

by Samantha McGrail

Sanofi and Translate Bio recently announced positive preclinical results for their mRNA-based COVID-19 vaccine candidate in mice. Specifically, the candidate called MRT5500 induced "potent"...

COVID-19 Antibody Cocktail Reduces Viral Levels, Regeneron Says

by Samantha McGrail

Regeneron Pharmaceuticals recently announced that its COVID-19 antibody cocktail reduced viral load and alleviated symptoms in non-hospitalized coronavirus patients in a Phase 1/2/3 clinical...

Abbott Enrolls First Patient in Spinal Cord Stimulation Study

by Samantha McGrail

Abbott recently announced the first patient has been enrolled in a study to investigate the efficacy of the company’s BurstDR spinal cord stimulation (SCS) in individuals with chronic low back...

ViiV Healthcare Launches Injectable HIV Treatment Study

by Samantha McGrail

ViiV Healthcare recently announced the start of a study that will evaluate the best approaches to implementing an investigational HIV treatment that needs to be injected into patients twice a...

Eli Lilly, Amgen Partner to Advance COVID-19 Antibody Therapies

by Samantha McGrail

Eli Lilly and Amgen recently announced a global manufacturing collaboration to increase the supply of Lilly’s potential COVID-19 antibody therapies.  If one or more of Lilly’s...

Early Data Shows Promise for Johnson & Johnson’s COVID-19 Vaccine

by Samantha McGrail

Johnson & Johnson recently announced early positive results from the ongoing Phase 1/2a clinical trial of its COVID-19 vaccine candidate. The results published in medRxiv, a preprint server for...

Bristol Myers Squibb Reports Breakthrough with Immunotherapy Opdivo

by Samantha McGrail

Bristol Myers Squibb recently announced that its immunotherapy, Opdivo (nivolumab), improved disease-free survival versus a placebo for patients with high-risk, muscle-invasive bladder cancer in a...

J&J Initiates Global Phase 3 Clinical Trial for COVID-19 Vaccine

by Samantha McGrail

Johnson & Johnson recently announced the launch of a large-scale, multi-country Phase 3 clinical trial for its COVID-19 vaccine candidate, JNJ,78436735. The ENSEMBLE trial will enroll nearly...

Global Effort Aims to Insure Against a Failed COVID-19 Vaccine

by Samantha McGrail

Sixty-four higher-income economies recently joined the COVAX Facility, a global COVID-19 response effort that ensures governments and manufacturers have access to COVID-19 vaccines, according to an...