Clinical Trials & Research News

GoodRx, Boehringer Increase Affordable Drug Access for Patients

by

GoodRx and Boehringer Ingelheim recently collaborated to increase affordable drug access for patients with type 2 diabetes or chronic obstructive pulmonary disease (COPD).   Under the...

Moderna Doses First Patient in Study of mRNA Therapeutic for MMA

by

Moderna recently announced that the first patient has received a dose in a Phase 1/2 study of its mRNA therapeutic, mRNA-3705, for methylmalonic acidemia (MMA).  The open-label landmark study...

FDA Authorizes Thermo Fisher’s PCR-Based COVID-19 Test Kits

by

FDA recently granted emergency use authorization for Thermo Fisher Scientific’s two PCR-based COVID-19 test kits. The test kits, TaqPath COVID-19 Fast PCR Combo Kit 2.0 and TaqPath COVID-19...

WHO Launches Next Trial Phase to Test COVID-19 Drugs in Patients

by

The World Health Organization (WHO) recently announced the next phase in its Solidarity trial, Solidarity PLUS, to test new COVID-19 drugs in hospitalized patients.  The trial will enroll...

FDA OKs 3rd COVID-19 Vaccine Dose for the Immunocompromised

by

FDA amends the emergency use authorizations for both the Pfizer-BioNTech and Moderna COVID-19 vaccines to allow for an additional dose in immunocompromised individuals. The agency determined that the...

Moderna Doses First Patient in Study of Autoimmune mRNA Candidate

by

Moderna recently dosed the first participant in the Phase 1 study of its autoimmune mRNA candidate, mRNA-6231, to expand regulatory T-cells. The trial is the first in-human, dose-escalation study to...

FDA Grants Fast Track to Moderna’s mRNA RSV Vaccine for Adults

by

Moderna recently announced that FDA granted Fast Track designation for its mRNA respiratory syncytial virus (RSV) vaccine, mRNA-1345, for use in adults 60 years of age and older. FDA Fast Track...

51% of Retail Pharmacy Customers Used Wellness Services in 2020-21

by

Over half of retail pharmacy customers (51 percent)  have used health and wellness services over the past year, according to the J.D. Powers 2021 US Pharmacy Study.  This number is up from...

FDA Expands Authorization of Regeneron’s COVID-19 Antibody Cocktail

by

FDA recently updated the emergency use authorization for Regeneron’s investigational COVID-19 antibody cocktail, REGEN-COV.  The authorization now includes post-exposure prophylaxis in...

Eli Lilly, Kumquat to Discover Drug Candidates for Tumors

by

Eli Lilly and Company and Kumquat Biosciences recently entered into a multi-year collaboration to discover, develop, and commercialize potential small molecule drug candidates that stimulate...

AstraZeneca, Regeneron to Develop Drug Candidates to Treat Obesity

by

AstraZeneca recently entered into a collaboration with Regeneron to research, develop, and commercialize small molecule drug candidates to treat obesity and related co-morbidities.  Specifically,...

Biogen’s Alzheimer’s Disease Drug Safe, Effective in Trial

by

Biogen recently announced that its Alzheimer’s disease drug, BIIB080, was safe and well-tolerated in patients with mild disease. The drug was developed in partnership with Ionis...

AbbVie, Calico Extend Partnership for Age-Related Disease Therapies

by

AbbVie and Calico Life Sciences recently extended their collaboration to discover, develop, and bring new therapies to market for patients with age-related diseases, including neurodegeneration and...

FDA Approves Merck’s Keytruda for Triple-Negative Breast Cancer

by

FDA recently approved Merck’s anti-PD-1 therapy, Keytruda, for the treatment of patients with high-risk, early-stage triple-negative breast cancer (TNBC) in combination with...

Pfizer, Arvinas to Develop Protein Degrader for Breast Cancer

by

Pfizer and Arvinas recently entered into a global collaboration to develop and commercialize an investigation oral PROteolysis Targeting Chimera (PROTAC) estrogen receptor (ER) protein degrader for...

High-Dose Buprenorphine Helped Untreated Opioid Use Disorder

by

High-dose buprenorphine induction was safe and well-tolerated in patients with untreated opioid use disorder, according to a JAMA Network Open study.  Researchers gathered data from electronic...

Lilly Enters Collaboration for Phase 3 Trial of Alzheimer’s Drug

by

Eli Lilly and Company and Banner Alzheimer’s Institute recently entered into a research collaboration as part of the planned Phase 3 clinical trial evaluating Lilly’s Alzheimer’s...

Pfizer Completes Trial Enrollment for Lyme Disease Vaccine

by

Pfizer and Valneva recently completed recruitment for the Phase 2 clinical trial of Lyme disease vaccine candidate, VLA15.  The trial, VLA15-221, builds on previous positive Phase 2 trials and...

Biogen, InnoCare Pharma Partner for Multiple Sclerosis Treatment

by

Biogen and InnoCare Pharma Limited recently entered into a license and collaboration agreement for orelabrutinib, a potential multiple sclerosis (MS) treatment. Orelabrutinib is a small molecule...

FDA Authorizes Ortho Clinical’s COVID-19 Antibody Test

by

FDA recently granted emergency use authorization to Ortho Clinical Diagnostics’ COVID-19 antibody test for use as an aid in identifying individuals with adaptive immune responses to the...