Clinical Trials & Research News

ACIP Recommends Pfizer’s TBE Vaccine For Individuals Most At Risk

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The CDC Advisory Committee on Immunization Practices (ACIP) recently recommended Pfizer’s tick-borne encephalitis (TBE) vaccine, TicoVac, to prevent TBE in individuals one year and older. ACIP...

Moderna, Thermo Fisher to Boost mRNA Vaccine Manufacturing

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Moderna and Thermo Fisher Scientific recently announced a 15-year collaboration agreement for dedicated large-scale manufacturing of Moderna’s COVID-19 vaccine and other mRNA vaccines in the...

Moderna, ROVI Expand Collaboration to Boost mRNA Vaccines

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Moderna and ROVI recently entered into a long-term collaboration to increase capacities for the compounding, aseptic filling, inspection, and manufacturing of mRNA vaccines and medicines over the next...

Merck’s Keytruda, Chemotherapy Helps High-Risk Breast Cancer

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Merck recently announced that Keytruda, combined with chemotherapy and followed by Keytruda as monotherapy, prolonged event-free survival compared to chemotherapy followed by placebo in patients with...

AstraZeneca’s Chemotherapy Treatment Improves Prostate Cancer

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AstraZeneca recently announced that its combination chemotherapy treatment improved radiographic progression-free survival (rPFS) compared to standard-of-care for metastatic castration-resistant...

Merck KGaA to Assess Quris AI Platform for Clinical Prediction

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Merck KGaA, Darmstadt, Germany, and Quris recently signed an agreement to assess the Quris BioAI machine learning platform and compare it to traditional in vitro and in vivo approaches. The Quris...

Biogen, Xbrane Develop Preclinical Monoclonal Antibody, Biosimilar

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Biogen and Xbrane Biopharma recently agreed to develop, manufacture, and commercialize a preclinical monoclonal antibody and proposed biosimilar, Xcimzane, referencing Cimzia.  Cimzia is a drug...

Abbott Implants Dual-Chamber Leadless Pacemaker in Clinical Trial

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Abbott recently announced the world's first implant of a dual-chamber leadless pacemaker system as part of its Aveir DR i2i pivotal clinical trial. The prospective investigational study will...

Pfizer Confirms Positive Date of Lyme Disease Vaccine Candidate

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Pfizer and Valneva recently announced further positive results from the Phase 2 clinical trial evaluating their Lyme disease vaccine candidate, VLA15. The trial, VLA15-221, enrolled 294 healthy adult...

Personalized Immunotherapy Could Treat Metastatic Breast Cancer

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Personalized immunotherapy from an individual’s tumor-fighting immune cells could potentially treat metastatic breast cancer, according to a study from the National Cancer Institute’s...

CVS Health, Medable Expand Clinical Trial Access, Engagement

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CVS Health and Medable recently collaborated to expand clinical trial access and engagement for patients at select MinuteClinic locations. The collaboration will combine Medable’s software...

Moderna, IAVI Dose First Patients in Trial of HIV Vaccine Antigens

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Modern and IAVI recently dosed the first two patients in a clinical trial of experimental HIV vaccine antigens at the George Washington University (GWU) School of Medicine and Health Sciences. The...

Opioid Use Disorder Medicine Lacking for Pregnant Women in US Jails

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Most pregnant and postpartum women with opioid use disorder (OUD) in US jails do not receive medication that is standard of care, a JAMA Network Open study found. The cross-sectional study surveyed...

AstraZeneca Combination Treatment Helps Advanced Biliary Tract Cancer

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AstraZeneca recently announced that Imfinzi combined with standard-of-care chemotherapy significantly improved overall survival and progression-free survival in patients with advanced biliary tract...

NIH Launches Competition to Boost Neuromodulation Therapies

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The National Institutes of Health (NIH) recently launched the first phase of Neuromod Prize, a $9.8 million competition to accelerate the development of neuromodulation therapies. Neuromodulation...

The Center for Breakthrough Medicines, UPenn Boost Gene Therapies

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The Center for Breakthrough Medicines (CBM) and the University of Pennsylvania Gene Therapy Program (GCP) recently collaborated to advance the discovery and manufacturing of gene therapies. The...

Moderna, Carisma Partner to Develop In Vivo Cancer Therapies

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Moderna and Carisma Therapeutics recently entered into an agreement to discover, develop, and commercialize in vivo engineered chimeric antigen receptor monocyte (CAR-M) cancer...

AstraZeneca to Discover Precision Medicines for Undruggable Targets

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AstraZeneca recently collaborated with Scorpion Therapeutics to discover, develop, and commercialize precision medicines against previously undruggable targets. The companies will focus on a class of...

Pfizer, Beam Focus on Precision Medicine for Rare Diseases

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Pfizer and Beam Therapeutics recently entered into a four-year collaboration focused on in vivo base editing programs to generate precision medicine for rare diseases of the liver, muscle, and central...

Bristol Myers, Century to Develop Allogeneic Cell Therapies

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Bristol Myers Squibb and Century Therapeutics recently collaborated to develop and commercialize up to four engineered natural killer (iNK) and/or allogeneic cell therapies for hematologic malignancies...