Clinical Trials & Research News

FDA Approves Drug for Open-Angle Glaucoma and Ocular Hypertension

by

In a recent press release, Santen announced that the FDA approved OMLONTI, the company’s newest ophthalmic medication. This ophthalmic solution is composed of 0.002% omidenepag isopropyl. This...

Fish Oil Supplements Associated with Risk of Atrial Fibrillation

by

Many vitamins and supplements are readily available over the counter for patient use. Understanding the effects of supplements on healthcare can impact and inform physician practices for more effective...

Pregnant and Lactating Individuals Tolerate COVID Vaccine Boosters

by

As new COVID boosters are approved and distributed, understanding how they affect pregnant and lactating individuals will impact public health policies, educational efforts, and provider distribution....

FDA and NIH Launch Partnership for Rare Neurodegenerative Diseases

by

Earlier this week, the FDA and NIH announced their launch of a public–private partnership for research on rare neurodegenerative diseases. The partnership, called the Critical Path for Rare...

Amgen’s Immunotherapy for Lung Cancer Reduces Disease Progression by 34%

by

Results from the Phase III CodeBreaK 200 clinical trial found that Amgen’s targeted therapy Lumakras successfully extended progression-free survival (PFS) by about two months and was 15% more...

Biden Administration Appoints Renee Wegrzyn as Director of the ARPA-H

by

The Advanced Research Projects Agency for Health (ARPA-H) was proposed by the Biden Administration on March 15, 2022, as a government organization to drive biomedical and healthcare innovation. Under...

Glucocorticoids Alter Brain Volume and White Matter Microstructure

by

Glucocorticoids are widely prescribed for those struggling with autoimmune and neurological conditions and are considered one of the most prescribed drugs. In a study published in BMJ Open, researchers...

Paxlovid Advantageous for Elderly COVID-19 Patients, Ineffective in Younger Adults

by

A study published on September 1st in the New England Journal of Medicine tracking health data from 109,254 Israeli adults found a 73% reduction in hospitalization and a 79% reduction in COVID-19...

Stroke Prevention Study to Analyze Benefits of Wearable Devices

by

Wearable devices have gained much traction recently for their potential uses in the healthcare industry. Recently, Northwestern University has collaborated with Johns Hopkins University on a research...

Fourth COVID Shot Reduced the Risk of Infection by 12.9%

by

While the general public may feel we are post-pandemic, healthcare workers know that COVID still runs rampant worldwide, especially in hospital settings. The recent study published in JAMA Network Open...

Antibiotic Overprescription Is Associated with Worse CKD Outcomes

by

A recent study in JAMA Open Network looked at the relationship between fluoroquinolone — an antibiotic — dosage and adverse side effects in patients with CKD. The researchers found that...

COVID-19 Vaccination Reduced the Risk of Reinfection by Approximately 50%

by

A cohort study in JAMA Network Open analyzed the efficacy of the COVID-19 vaccine in preventing SARS-CoV-2 reinfection. The study found that COVID-19 vaccination reduced reinfection rates by...

Astellas and Seagen Announce Results on a Drug for Urothelial Cancer

by

According to a recent press release, Astellas and Seagen have teamed up to develop a combined treatment for urothelial cancer in patients who are ineligible to receive cisplatin chemotherapy. The new...

Decreased COVID-19 Vaccination Rates: A Pediatric Health Risk

by

The Kaiser Family Foundation (KFF) recently found that pediatric COVID-19 vaccination rates in children under 5 years old have decreased despite the age bracket’s very recent eligibility....

FDA Grants Abbott Permission to Investigate DBS in Managing Depression

by

Abbott recently announced that they had been granted Breakthrough Device Designation by the FDA, which allows them to investigate the use of deep brain stimulation (DBS) in managing severe...

Verve Doses First Patient with Investigational Gene-Editing Medicine

by

A recent statement by Verve Therapeutics announced the start of the phase 1b clinical trial on heterozygous familial hypercholesterolemia (HeFH) in New Zealand. This announcement highlighted the first...

Decentralization Tools May Improve Cancer Clinical Trial Enrollment

by

According to a cross-sectional survey study published in JAMA, remote and decentralization tools can improve clinical trial enrollment and participation in cancer studies.  Recently, many...

Decibel Therapeutics Announces Results of DB-020 Clinical Trial

by

At the end of June, Decibel Therapeutics announced success in the phase 1b clinical trials on DB-020 for cancer patients receiving cisplatin chemotherapy. DB-020 is a sodium thiosulfate (STS) drug...

FDA Approves New Treatment for Large B-Cell Lymphoma

by

Recently, the FDA approved a new second-line treatment for large B-cell lymphoma (LBCL). Lisocabtagene maraleucel is the generic name for Breyanzi, developed and marketed by Juno Therapeutics. As a...

FDA Approves New Weight Management Drug for Kids over 12

by

Recently, the FDA approved Qsymia for chronic weight management in pediatric patients over 12 years old. Qsymia is an extended-release pill composed of phentermine and topiramate. The drug’s...